Yes, you can follow the below steps to hide a full partition
1. Type diskmgmt.msc in Run
2. Right click on the partition you want to hide
3. and select Change Drive letter and paths
4. In that Click Remove. The removed partition will not be displayed on your my computer (note: it will not delete your data)
To Enable
Follow First 3 Steps and click on add and set the drive letter.
Thank you...